There are many Factors Affecting in the EO Gas Sterilization Process, pls view the following:

1. 氣體濃度

• 在一定的氣體濃度範圍內，濃度越高，EO氣體滅菌效果越好；超過1000mg/L，滅菌效果改善不顯著。

2.相對濕度

• 相對濕度在40%-80%之間時，滅菌效果無明顯差異；低於40%，殺菌效果明顯下降； 90%以上，沒有明顯改善，且容易產生水滴，對殺菌產生不利影響。

3. Temperature

• At temperatures between 30-65°C, for every increase of 10°C, the EO Gas Sterilization effect doubles; above 65°C, there is no significant improvement in sterilization effect.

時間

• Higher ETO concentration requires a shorter action time; lower ETO concentration requires a longer action time.

存活機率

• The longer the EO Gas Sterilization time, the lower the survival probability of microorganisms in the product (better sterilization effect).
• The EO Gas Sterilization time has a linear relationship with the logarithm of the number of surviving microorganisms (this is the most important theoretical support for determining mortality rate).

Other Influencing Factors

產品特點

1. Product Materials and Structure:
   • 結構影響氣體進出； some materials are unsuitable for ethylene oxide sterilization, and certain materials need to absorb more moisture/heat.
2. 包裝材料。
3. Initial Contamination:
   • Initial quantity and types of contaminating bacteria in the product (methods such as residual probability and direct counting have requirements for initial contamination levels; some products have endotoxin requirements; some microorganisms exhibit resistance to ethylene oxide).

Process Operations

1. Vacuum Level:
   • Affects gas diffusion and penetration, impacts the concentration of gas acting on the product;影響包裝安全與產品安全； influences displacement effectiveness and residue.
2. Loading Conditions:
   • Affects heat/wet penetration and distribution; influences gas circulation.

如果您想了解更多有關氧化乙烷滅菌的信息

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